For those who have database-like applications, FileMaker may be another
possible option after FB. I have a bunch of FileMaker databases to
coordinate images and attributes for my paleontological/biostratigraphic
work. FileMaker scripts allow limited programming within and between these
databases. FileMaker Advanced (formerly FileMaker Developer) allows the
creation of stand-alone database applications.

I mention it here because the newest versions, 10 and now 11, provide some
new user events, in addition to button-clicks and menu items to trigger
scripts.

While it is not a tool to compete with the likes of FB, RB, C, Java, etc.,
it may be a good solution for some aspects of your work.